Currin was born in Boulder, Colorado, and grew up in Connecticut, where he studied painting privately with a renowned traditionally trained artist from Odessa, Ukraine, Lev Meshberg. He went to Carnegie Mellon University in Pittsburgh, where he obtained a BFA in 1984, and received a MFA from Yale University in 1986.
In New York City in 1989 he exhibited a series of portraits of young girls derived from the photographs in a high school yearbook, and initiated his efforts to distill art from traditionally clichéd subjects. In the 1990s, when political themed art works were favored, Currin brazenly used bold depictions of busty young women, mustachioed men and asexual divorcés, setting him apart from the rest. He used magazines like Cosmopolitan along with old issues of Playboy for inspiration for his paintings. When criticized for being sexist, Currin did not deny it, but did remark that he felt that "at that time didn't feel like a man and didn't feel like a woman." In 1992 a subsequent exhibition focused, less sympathetically, on well-to-do middle-aged women. Nonetheless, by the late 1990s Currin's ability to paint subjects of kitsch with technical facility met with critical and financial success, and by 2003 his paintings were selling "for prices in the high six figures". More recently, he has undertaken a series of figure paintings dealing with unabashedly pornographic themes.

He has had retrospective exhibitions at the Whitney Museum of American Art and the Museum of Contemporary Art, Chicago and is represented in the permanent collections of the Hirshhorn Museum and Sculpture Garden and the Tate Gallery.
John Currin 1962-ben született.
Mindazonáltal, a kései 1990-es években Currin képessége, hogy giccses témákat fessen magas szintű technikai adottsággal, találkozott a kritikai és anyagi sikerrel, és 2003-ra a festményei hat számjegyű összegekért keltek el. Mostanában figurális sorozatok festésébe kezdett, amelyek szégyentelenül pornografikus témájúak. A Whitney Museum of American Art-ban és a Chicago-i Museum of Contemporary Art-ban volt retrospektív kiállítása, és állandó gyűjteményekben vannak munkái a Hirshhorn Museum and Sculpture Garden-ben és a Tate Galériában. Currin jelenleg New York-ban él feleségével Rachel Feinstein-nel (aki egyben művésztársa).